Malaria resistance in Guyana, South America

Two imported cases of Chloroquine-, Fansidar-, and quinine-resistant Plasmodium falciparum malaria were diagnosed and treated in Trinidad, West Indies. The infections were cured by the administration of a multiple drug treatment regime of 45 mg Primaquine phosphate, 1.8 g sulphadoxine, 75 mg Pyrimethamine (Fansidar), and 650 mg quinine sulphate. Recrudescence has not occurred over the past 30 months. (AU)